Match treatment to mechanism.
Etiolinks identifies the underlying drivers of persistent conditions, enabling more precise, effective care decisions from the outset.
Developed from clinical work in chronic pain and informed by multidisciplinary practice.
Recommended
PNE + Graded Activity
A growing problem with no systematic solution
Persistent pain is one of the most common and costly presentations in healthcare.
$635B+
Annual US chronic pain cost
$8K–$15K
Average per-patient pathway cost
< 40%
Achieve even moderate improvement
Across healthcare systems, patients with persistent pain follow a recognisable pattern:
- Repeated consultations without resolution
- Imaging and specialist referral that do not explain symptoms
- Escalating pharmacological management
- Ongoing functional limitation
This is not a failure of effort. It is a failure of alignment.
When the pathway is wrong, everything that follows is compromised.
What changes when the pathway is aligned
The first decision determines everything that follows.
Current Pathway
- Symptoms → imaging → medication → referral → repeat
- No clear explanation
- Escalating cost
- Persistent symptoms
$8,000–$15,000+
per patient
Etiolinks-Aligned Pathway
- Early identification of what is maintaining symptoms
- Targeted intervention aligned with mechanism
- Reduced escalation and unnecessary investigation
- Improved functional trajectory
$1,500–$4,000
per patient
When the pathway is aligned early, outcomes improve and avoidable cost is reduced.
Identifying what is maintaining symptoms
Identify what is maintaining symptoms. Align care accordingly.
Etiolinks applies structured clinical reasoning to identify the factors driving symptom persistence. The system encodes patterns of clinical judgement that are typically applied inconsistently — making them available early and at scale.
Pain Classification
Determines the likelihood of nociplastic, nociceptive, and neuropathic drivers — enabling mechanism-based rather than symptom-based care decisions.
Clarity before care
Clinical application
From presentation to pathway in under a minute.
In this example, you will see how a patient at risk of ongoing escalation is identified, how the system determines what is maintaining symptoms, what pathway is recommended, and what interventions are unlikely to improve outcomes.
View Clinical Demo →This patient is on a pathway unlikely to lead to recovery.
Further medical escalation is unlikely to improve outcomes.
Recommended
Early redirection to neuroplastic care pathway
Confidence: High
Designed for decision-makers at key points in care
Not all pain is the same. Care shouldn't be either.
Clinicians
Make earlier, more confident decisions in complex cases
- Identify patients unlikely to respond to further escalation
- Reduce uncertainty in persistent pain presentations
- Avoid ineffective or low-value interventions
Payers / Health Systems
Reduce avoidable cost in high-utilisation patients
- Identify patients at risk of escalation early
- Reduce imaging, referrals, and medication burden
- Improve allocation of care resources
Patients
Understand why pain persists — and what to do next
- Clear explanation of what is maintaining symptoms
- Structured pathway forward
- Reduced trial-and-error care
The cost of pathway mismatch
Current Pathway
Repeated consultations, imaging, and medication escalation without meaningful improvement.
$8,000–$15,000+
estimated cost per patient
Etiolinks-Aligned Pathway
Early identification and targeted intervention with reduced reliance on low-yield investigation.
$1,500–$4,000
estimated cost per patient
Without early alignment, patients remain in high-cost cycles of care. Early redirection reduces utilisation while improving the likelihood of recovery.
Frequently Asked Questions
EtioLinks is a clinical decision support system designed to guide pathway decisions in persistent conditions. It generates structured clinical reasoning, models why patients aren't improving, and aligns care with what is actually maintaining symptoms. The system encodes patterns of clinical judgement that are typically applied inconsistently — making them available early and at scale.
PainMap is the first application of the EtioLinks engine, focused on chronic pain. It identifies what's likely driving a patient's pain, explains why it has persisted, and recommends a matched intervention. In minutes, not months. At the point of assessment, the system provides pain classification, clinical pattern identification, a decision summary, a recommended care pathway, and treatment risk flags.
No. Etiolinks does not replace clinical judgement. It supports it by making implicit reasoning explicit and consistent. Clinicians can override any recommendation at any time. The system augments physician thinking, helps with workload, and gives clinicians back the time for deeper human connection with their patients.
PainMap currently covers chronic pain. The EtioLinks engine is expanding to IBS, pelvic pain, migraine, fatigue syndromes, and other conditions where symptoms and findings do not align — and early decisions determine long-term outcomes. Same reasoning architecture applied across chronic disease.
Etiolinks is not a diagnostic replacement, a standalone treatment, or a wellness or self-help tool. It is a clinical decision support system designed to guide pathway decisions in persistent conditions. It does not generate diagnoses, prescribe treatment, or replace the clinical relationship.
Etiolinks is designed for primary care referral triage and digital health clinics that need to show better outcomes at lower cost. It solves the problem upstream — making it attractive to payers, providers, and patients. By reducing unnecessary imaging, referrals, and medication escalation, the system creates measurable cost savings at the system level.
Change the decisions that keep patients stuck in pain
Identify high-risk patients earlier. Avoid ineffective pathways. Improve outcomes while reducing cost.